Antifungal efficacy of chitosan nanoparticles against phytopathogenic fungi and inhibition of zearalenone production by Fusarium graminearum

  • Hanem A. Abdel-Aliem
  • Ahmed Y. Gibriel
  • Nagwa M. H. Rasmy
  • Ahmed F. Sahab
  • Aziza A. El-Nekeety
  • Mosaad Attia Abdel-Wahhab Food Toxicology & Contaminants Dept., National Research Center, Dokki, Cairo

Abstract

Chitosan (COS) is a natural safe biopolymer that received great attention in agriculture, food, biomedical, pharmaceutical and environmental industries because their biocompatible, biodegradable, non-toxic and non-allergenic natures. The aims of the current study were to synthesize and characterize chitosan nanoparticles (COS-NPs), to evaluate their antifungal activity against phytopathogenic fungi and inhibition of zearalenone (ZEN) production by Fusarium graminearum. The results revealed that the deacetylation degree of COS was 86.9 0.44 %, the average of molar mass was 171.41 ± 0.29 g/mol, molecular weight was 244 ± 7 kDa and the concentration of free amino groups was 0.05 ± 0.019 mol L-1. COS-NPs showed the nanorod form with rough nature and particle size was around 180 nm. COS-NPs showed an excellent antifungal activity against Alternaria tenuis, Aspergillus niger, A. flavus, Baeuvaria bassiana, Fusarium graminearum, Fusarium oxysporum, Penicillium sp. and Sclerotium rolfsii in dose dependent manner. At a concentration of 800 ppm, it inhibits ZEN production by Fusarium graminearum. It could be concluded that COS-NPs are promise candidate as safe antifungal capable for the prevention of ZEN production.

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Author Biography

Mosaad Attia Abdel-Wahhab, Food Toxicology & Contaminants Dept., National Research Center, Dokki, Cairo
Toxicology & Food Safety

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Published
31-10-2019
How to Cite
Abdel-Aliem, H., Gibriel, A., Rasmy, N., Sahab, A., El-Nekeety, A., & Abdel-Wahhab, M. (2019). Antifungal efficacy of chitosan nanoparticles against phytopathogenic fungi and inhibition of zearalenone production by Fusarium graminearum. Comunicata Scientiae, 10(3), 338-345. https://doi.org/10.14295/cs.v10i3.1899
Section
Original Article